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Arch Dis Child Fetal Neonatal Ed 88:F531-F533 doi:10.1136/fn.88.6.F531
  • Case report

Congenital idiopathic chylothorax in neonates: chemical pleurodesis with povidone-iodine (Betadine)

Table 1

Intrapleural instillation of Betadine

Case No Antenatal diagnosis Diagnosis Type of Betadine Number and time of instillations Volume (ml) of Betadine, child’s weight (g) Duration of post-instillation chest tube occlusion (h) Maximal analgesia (μg/kg/h) Outcome (chest tube removal) Adverse effect Thyroid function
ND, Not done; L, left; R, right; CIC, congenital idiopathic chylothorax.
1 Yes CIC Scrub R: 1 (day 65) 10,<•> 4 Fentanyl (10) Successful (16 days) None Normal before and 19 days after instillation
2500
2 Yes CIC Scrub R: 1 (day 11)<•> 5 per instillation,<•> Right side: 2<•> Fentanyl (10) Successful (10 days) Increase in contralateral pleural effusion after the first instillation of Betadine Normal before and 16 days after instillation
L: 1 (day 13) 2200 Left side: 3
3 Yes CIC Dermique R: 1 (day 59) 3,<•> 3 Sufentanyl (0.8) Successful (6 days) Generalised oedema 24 hours after instillation (spontaneous resolution) Normal before and 30 days after instillation
3000
4 Yes Diffuse lymphangectasia Scrub L: 2 (days 22 and 26)<•> 5 per instillation,<•> 5 Fentanyl (10) Failure Increase in contralateral pleural effusion after the first instillation of Betadine ND
R: 1 (day 25) 3100

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