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Arch Dis Child Fetal Neonatal Ed 89:F168-F173 doi:10.1136/adc.2002.023796
  • Original article

Clinical detection of low upper body blood flow in very premature infants using blood pressure, capillary refill time, and central-peripheral temperature difference

Table 4

Diagnostic accuracy of mean and systolic blood pressure for prediction of low superior vena cava flow in preterm infants < 30 weeks gestation

Sn Sp PPV NPV LR+ LR−
Values in parentheses are 95% confidence intervals.
BP, Blood pressure; LR+, positive likelihood ratio; LR−, negative likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; Sn, sensitivity; Sp, specificity.
Systolic BP < 48 mm Hg
    3 hours 100 (100 to 100) 14 (7 to 21) 15 (8 to 22) 100 (100 to 100) 1.17 0
    10 hours 92 (87 to 97) 39 (30 to 49) 44 (35 to 54) 90 (85 to 96) 1.52 0.21
    All observations 93 (90 to 96) 35 (30 to 41) 24 (19 to 28) 96 (93 to 98) 1.43 0.21
Systolic BP < 40 mm Hg
    3 hours 69 (60 to 78) 51 (41 to 61) 18 (10 to 26) 91 (86 to 97) 1.42 0.60
    10 hours 81 (74 to 88) 65 (56 to 74) 55 (45 to 64) 87 (80 to 93) 2.30 0.29
    All observations 76 (71 to 81) 68 (62 to 73) 34 (28 to 39) 93 (90 to 96) 2.35 0.36
Mean BP < 30 mm Hg
    3 hours 62 (57 to 71) 58 (49 to 68) 19 (11 to 26) 91 (85 to 97) 1.48 0.66
    10 hours 62 (53 to 71) 82 (74 to 89) 64 (55 to 73) 81 (73 to 88) 3.40 0.46
    All observations 59 (54 to 65) 77 (72 to 82) 36 (30 to 41) 90 (86 to 93) 2.56 0.53
Mean BP ⩽ gestation (in weeks) mm Hg
    3 hours 38 (29 to 48) 76 (68 to 85) 20 (12 to 28) 89 (83 to 95) 1.62 0.81
    10 hours 27 (19 to 35) 92 (86 to 97) 63 (53 to 72) 71 (62 to 79) 3.2 0.8
    All observations 30 (25 to 35) 88 (84 to 91) 34 (29 to 39) 85 (81 to 89) 2.40 0.80

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