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Arch Dis Child Fetal Neonatal Ed 89:F263-F268 doi:10.1136/adc.2002.025635
  • Original article

Cost effectiveness analysis of neonatal extracorporeal membrane oxygenation based on four year results from the UK Collaborative ECMO Trial

Table 4

Incremental cost effectiveness ratios (UK£ sterling, 2001 prices)

Cost and outcome measure Mean 95% CI*
*Non-parametric bootstrap estimation was performed using 1000 replications, bias corrected.
Incremental cost per additional life year gained 16707 9828 to 37924
Sensitivity analyses for principal outcome
(a) Hospital costs
    (1) 20% reduction in daily costs 13713 7792 to 31916
    (2) 20% increase in daily costs 19701 11327 to 46923
(b) Community service use
    (1) 10% greater than reported 16732 10004 to 41649
    (2) 20% greater than reported 16757 10172 to 38593
    (3) 30% greater than reported 16782 9849 to 38839
(c) Discount rates applied to years 1–4
    (1) Costs discounted at 0% 16716 10240 to 39779
    (2) Costs discounted at 3% 16715 9669 to 38386
    (3) Costs discounted at 10% 16712 9911 to 39529
    (4) Life years discounted at 0% 16101 9406 to 33411
    (5) Life years discounted at 3% 17248 10530 to 38602
    (6) Life years discounted at 6% 18458 10674 to 40623
Incremental cost per additional disability-free life year gained 24775 13106 to 69690
Sensitivity analyses for secondary outcome
(a) Hospital costs
    (1) 20% reduction in daily costs 20335 10835 to 55870
    (2) 20% increase in daily costs 29215 16047 to 84105
(b) Community service use
    (1) 10% greater than reported 24812 13722 to 71204
    (2) 20% greater than reported 24850 13831 to 70149
    (3) 30% greater than reported 24887 13440 to 72299
(c) Discount rates applied to years 1–4
    (1) Costs discounted at 0% 24789 13190 to 71989
    (2) Costs discounted at 3% 24787 13155 to 74445
    (3) Costs discounted at 10% 24783 13700 to 70811
    (4) Disability-free life years discounted at 0% 23879 12098 to 73504
    (5) Disability-free life years discounted at 3% 25697 13874 to 71822
    (6) Disability-free life years discounted at 6% 27568 15045 to 90608

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