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Arch Dis Child Fetal Neonatal Ed 89:F300-F304 doi:10.1136/adc.2003.033555
  • Original article

A randomised controlled trial of morphine versus phenobarbitone for neonatal abstinence syndrome

Table 1

 Clinical characteristics of the infants studied and classes of drugs used by their mothers

Oramorph (n = 41) Phenobarbitone (n = 34)
Where applicable, values are mean (range).
Gestational age (weeks) 40 (32–42) 39 (33–41)
Birth weight (g) 2960 (1760–3930) 2780 (1860–3760)
Age randomised (hours) 48 (12–120) 48 (12–240)
Breast fed (%) 4.9 5.9
Methadone dose (mg) 30 (5–65) 35 (10–100)
    Interquartile range 15–49 24–51
Opiate exposed (%) 100 100
Benzodiazepine exposed (%) 22 44
Exposed to other drug classes (%) 10 23
Apgar 1 minute 9 (5–10) 9 (4–9)
Apgar 5 minutes 10 (8–10) 9 (6–10)

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