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Arch Dis Child Fetal Neonatal Ed 89:F384-F388 doi:10.1136/adc.2002.025114
  • Review

Early developmental care for preterm neonates: a call for more research

Table 1

 Impact of NIDCAP on selected outcome variables

No of RCTs Reference No of infants MD RR 95% CI
Modified from Symington and Pinelli9 and Jacobs et al.45
RCT, Randomised controlled trial; MD, mean difference; RR, relative risk; CI, confidence interval; IVH, intraventricular haemorrhage; BPD, bronchopulmonary dysplasia (radiographic changes).
Duration (days)
    Ventilation 2 45 (42, 43) 73 −27.7 −43.9 to −7.5
    Supplementary oxygen 2 45 (42, 44) 59 −41.1 −65.3 to −16.8
Moderate-severe BPD 2 32 (42, 44) 31 0.34 0.15 to 0.81
IVH ⩾ grade 3 3 42–44 98 0.51 0.23 to 1.10
Neurodevelopment at 9–12 months
    Cognitive 3 45 (42–44) 79 16.6 9.3 to 23.8
    Motor 3 45 (42–44) 79 9.2 0.7 to 17.8

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