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Arch Dis Child Fetal Neonatal Ed 90:F46-F48 doi:10.1136/adc.2003.042747
  • Original article

Benefit of antenatal glucocorticoids according to the cause of very premature birth

Table 2

 Neonatal outcome according to antenatal glucocorticoid treatment and cause of preterm delivery: multiple logistic regression

RDS BPD at 28 days BPD at 36 weeks Hospital death
aOR 95% CI p Value aOR 95% CI p Value aOR 95% CI p Value aOR 95% CI p Value
The multiple logistic regression includes antenatal glucocorticoid treatment, cause of preterm delivery, gestational age, sex, year, and centre.
BPD, bronchopulmonary dysplasia; IUGR, intrauterine growth restriction; PROM, prolonged rupture of the membranes; RDS, respiratory distress syndrome; aOR, adjusted odds ratio.
Antenatal glucocorticoids 0.04 0.23 0.28 0.12
    No 1.00 1.00 1.00 1.00
    Yes 0.67 0.45 to 0.99 0.73 0.43 to 1.23 0.69 0.34 to 1.37 0.66 0.39 to 1.12
Cause of preterm delivery <0.001 0.007 0.01 0.41
    Chorioamnionitis 1.00 1.00 1.00 1.00
    PROM 0.81 0.47 to 1.42 0.90 0.42 to 1.93 1.13 0.44 to 2.92 0.58 0.28 to 1.20
    Pre-eclampsia 7.16 3.85 to 13.3 1.91 0.88 to 4.12 0.80 0.25 to 2.49 0.76 0.35 to 1.68
    IUGR 3.13 1.96 to 5.01 2.81 1.50 to 5.32 2.86 1.27 to 6.46 1.17 0.63 to 2.16
    Other 3.25 2.00 to 5.30 1.28 0.64 to 2.55 0.59 0.21 to 1.72 0.80 0.42 to 1.54

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