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Arch Dis Child Fetal Neonatal Ed 90:F270-FF272 doi:10.1136/adc.2004.062380
  • Short report

Autopsy after death due to extreme prematurity

Table 3

 Iatrogenic lesions found at autopsy in extremely preterm infants dying before 28 days of age

GA (weeks) Age at death (days) Iatrogenic lesion Diagnosis made pre-mortem Lesion cause of death?
TPN, Total parenteral nutrition.
25 15 Transection of trachea Yes Yes
25 8 Chorioamnionitis secondary to amnio-infusion No No
congenital pneumonia
27 8 Cardiac tamponade due to long line Uncertain Yes
23 10 Perforation of stomach by orogastric tube No No
27 8 Aortic thrombus associated with umbilical catheter Yes Yes
23 2 Haemorrhage around the right umbilical artery associated with catheter insertion No No
25 19 Perforation of left subclavian vein with long line catheter Yes Yes
25 19 Oesophagus: multiple linear abrasions with haemorrhage No No
24 8 Thrombus right umbilical artery to above the aortic bifurcation No No
25 20 TPN related cholestasis No No
24 1 Injury to lung and heart secondary to needle aspiration of pneumothoraces Heart known to have been punctured No
27 9 Oesophageal ulceration. Gastric ulceration. TPN related cholestasis No No

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