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Arch Dis Child Fetal Neonatal Ed 90:F343-FF344 doi:10.1136/adc.2004.062588
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Nasal continuous positive airway pressure: does bubbling improve gas exchange?

Table 1

 Effect of bubbling rate on Tcco2, TcPo2, Spo2, heart rate, and respiratory rate

Vigorous, high amplitude bubbling Slow bubbling p Value
Values are mean (SD).
CPAP (cm H2O) 5.98 (1.3) 5.28 (1.2) <0.001
Tcco2 (mm Hg) 50 (17) 51 (18) 0.30
TcPo2 (mm Hg) 70 (18) 69 (17) 0.27
Spo2 (%) 95 (4) 95 (4) 0.67
Heart rate (beats/min) 154 (10) 156 (9) 0.47
Respiratory rate (breaths/min) 44 (15) 43 (16) 0.66

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