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Arch Dis Child Fetal Neonatal Ed 2006;91:F153 doi:10.1136/adc.2004.066431
  • LETTER

Neonatal effects of exposure to selective serotonin reuptake inhibitors during pregnancy

  1. P Bot1,
  2. B A Semmekrot1,
  3. J van der Stappen2
  1. 1Department of Paediatrics, Canisius-Wilhelmina Hospital, PO Box 9015, 6500 GS Nijmegen, the Netherlands
  2. 2Department of Clinical Chemical Analysis, Canisius-Wilhelmina Hospital
  1. Correspondence to:
    Dr Semmekrot
    B.Semmekrot{at}cwz.nl

    Selective serotonin reuptake inhibitors (SSRIs) are often prescribed during pregnancy.

    It has long been debated whether adverse neonatal effects described after maternal SSRI use1–4 are caused by serotonin toxicity or withdrawal.5 Recently, the information of a database analysis of 93 suspected cases of SSRI induced neonatal withdrawal has been regarded as enough information to confirm a possible causal relation.6

    We describe six infants with neonatal symptoms …

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