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Arch Dis Child Fetal Neonatal Ed 2006;91:F226-F230 doi:10.1136/adc.2005.082271
  • Review

Minimising ventilator induced lung injury in preterm infants

  1. S M Donn1,
  2. S K Sinha2
  1. 1Division of Neonatal-Perinatal Medicine, C S Mott Children’s Hospital, University of Michigan Health System, Ann Arbor, MI, USA
  2. 2Department of Paediatrics and Neonatology, The James Cook University Hospital, University of Durham, Middlesbrough, UK
  1. Correspondence to:
    Professor Donn
    F5790, C S Mott Children’s Hospital, 1500 E Medical Center Drive, Ann Arbor, MI, USA 48109-0254; smdonnmd{at}med.umich.edu
  • Accepted 15 November 2005

Abstract

Ventilator induced lung injury continues to occur at an unacceptably high rate, which is inversely related to gestational age. Although the “new BPD” may not be entirely avoidable in the extremely premature infant, recognition of risk factors and adoption of an appropriate ventilatory strategy, along with continuous real time monitoring, may help to minimise lung damage. This paper will review the pathogenesis of ventilator induced lung injury and strategies that may mitigate it.

Footnotes

  • Competing interests: none declared

Responses to this article

  • Targeting the inflation limb does not result in optimal ventilation
    • David G Tingay,
    • John F. Mills, Colin J. Morley, Anastasia Pellicano and Peter A Dargaville
    Arch Dis Child - Fetal Neonatal Ed published online May 31, 2006

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