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Arch Dis Child Fetal Neonatal Ed 2006;91:F233 doi:10.1136/adc.2005.086702
  • LETTER

Nasal nitric oxide to diagnose primary ciliary dyskinesia in newborns

  1. F Stehling,
  2. C Roll,
  3. F Ratjen,
  4. H Grasemann
  1. Children’s Hospital, University of Duisburg-Essen, Essen, Germany
  1. Correspondence to:
    Dr Grasemann
    The Hospital for Sick Children, Division of Respiratory Medicine, 555 University Ave, Toronto, Ontario, Canada M5G 1XA; hartmut.grasemann{at}sickkids.ca

    Retrospective data suggest that approximately half of patients with primary ciliary dyskinesia (PCD) have symptoms of neonatal respiratory distress. Respiratory distress syndrome in a full term infant should therefore raise PCD as a potential underlying disease.1,2 The non-invasive measurement of nasal nitric oxide (NO) is of diagnostic value in adults and children with PCD,1,3 but similar information is not available for neonates with PCD.

    A 3550 g male infant was delivered after uncomplicated …

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