Palliation bias is being overlooked in neonatal hypothermia trials
- Department of Neonatology, Sunnybrook and Women’s College Health Sciences Centre, Toronto, Canada
- Correspondence to:
A J A Ziino
Department of Neonatology, Sunnybrook and Women’s College Health Science Centre, Toronto, Canada;adrianziino{at}rogers.com
I thank Edwards and Azzopardi for their review1 of the trials on therapeutic hypothermia after perinatal asphyxia.2–4 Unfortunately, the evaluation of data quality fails to acknowledge a major shortcoming common to all three reported trials—“palliation bias”. A clear palliation bias in the …
