Angiotensin-converting enzyme inhibitor fetopathy: long-term outcome
- 1Nephrology Unit, University Children’s Hospital Zurich, Switzerland
- 2Children’s Hospital Lucerne, Switzerland
- Dr Guido F Laube, University Children’s Hospital, Steinwiesstrasse 75, CH-8032 Zurich, Switzerland; guido.laube{at}kispi.unizh.ch
- Accepted 31 December 2006
- Published Online First 6 February 2007
Abstract
Fetal exposure to angiotensin-converting enzyme inhibitors (ACEIs) is associated with increased neonatal morbidity and mortality. Long-term follow-up of three patients with fetal ACEI exposure revealed impaired renal function in two, severe hypertension and proteinuria in one and isolated polycythaemia in all three. Careful long-term follow-up of children with ACEI fetopathy is recommended.
- angiotensin-converting enzyme inhibitor
- fetopathy
- neonatal renal failure
- long-term outcome
- polycythaemia
Footnotes
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Competing interests: None.
- Abbreviations:
- ACEI
- angiotensin-converting enzyme inhibitor
- GFR
- glomerular filtration rate
