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Arch Dis Child Fetal Neonatal Ed 93:F115-F120 doi:10.1136/adc.2007.123745
  • Original article

A cohort study of low Apgar scores and cognitive outcomes

Table 3 Logistic regression models for the association of duration to achieve a normal Apgar score and poor score at cognitive testing
Time to reach an Apgar score of >6 (min) Measures of cognition Measure of educationLow school grade(n = 167 117)
Low logic score(n = 134 596) Low synonym score(n = 133 858) Low spatial score(n = 133 825) Low technical score(n = 124 149) Low IQ score(n = 136 788)
OR (95% CI) p* OR (95% CI) p* OR (95% CI) p* OR (95% CI) p* OR (95% CI) p* OR (95% CI) p*
Unadjusted
<1 1.00 1.00 1.00 1.00 1.00 1.00
1–5 1.20 (1.05 to 1.38) 0.001 1.04 (0.91 to 1.19) 0.11 1.01 (0.89 to 1.15) 0.05 1.19 (1.04 to 1.36) 0.02 1.09 (0.98 to 1.21) 0.008 0.89 (0.80 to 1.00) 0.60
>5 1.43 (1.05 to 1.94) 1.30 (0.98 to 1.74) 1.47 (1.12 to 1.93) 1.13 (0.83 to 1.54) 1.30 (1.04 to 1.64) 1.20 (0.95 to 1.51)
Adjusted for antenatal†§ factors
<1 1.00 1.00 1.00 1.00 1.00 1.00
1–5 1.26 (1.10 to 1.44) <0.001 1.10 (0.96 to 1.25) 0.03 1.03 (0.91 to 1.18) 0.03 1.19 (1.04 to 1.37) 0.02 1.12 (1.01 to 1.25) 0.002 0.95 (0.85 to 1.06) 0.86
>5 1.43 (1.06 to 1.94) 1.33 (1.00 to 1.79) 1.45 (1.11 to 1.91) 1.09 (0.80 to 1.49) 1.31 (1.04 to 1.65) 1.24 (0.98 to 1.56)
Adjusted for antenatal† and intrapartum/neonatal factors‡
<1 1.00 1.00 1.00 1.00 1.00 1.00
1–5 1.26 (1.10 to 1.44) <0.001 1.11 (0.97 to 1.27) 0.01 1.03 (0.90 to 1.17) 0.03 1.20 (1.05 to 1.38) 0.02 1.14 (1.03 to 1.27) 0.001 0.98 (0.89 to 1.08) 0.80
>5 1.43 (1.06 to 1.94) 1.36 (1.02 to 1.82) 1.46 (1.11 to 1.91) 1.09 (0.80 to 1.49) 1.35 (1.07 to 1.69) 1.10 (0.89 to 1.36)
Adjusted for antenatal†, intrapartum/neonatal factors‡ and social factors§
<1 1.00 1.00 1.00 1.00 1.00 1.00
1–5 1.25 (1.10 to 1.43) <0.001 1.09 (0.96 to 1.25) 0.04 1.02 (0.90 to 1.16) 0.08 1.18 (1.04 to 1.35) 0.04 1.14 (1.03 to 1.27) 0.003 0.96 (0.87 to 1.06) 0.61
>5 1.34 (1.01 to 1.78) 1.26 (0.95 to 1.67) 1.37 (1.05 to 1.77) 1.03 (0.77 to 1.39) 1.35 (1.07 to 1.69) 1.01 (0.81 to 1.26)
  • *p for trend.

  • †Parity, pre-eclampsia, birth weight, length and head circumference.

  • ‡Mode of delivery, maternal or infant infection, season and year of birth.

  • §Maternal and paternal education status, occupation and age.

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