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Arch Dis Child Fetal Neonatal Ed 93:F257-F260 doi:10.1136/adc.2007.120691
  • Original article

N-terminal pro-B-type natriuretic peptide: a measure of significant patent ductus arteriosus

Table 1 Effect of independent variables (gestational age, prolonged rupture of membrane (PROM), inotropes, sepsis and significant patent ductus arteriosus (PDA)) on plasma NT-proBNP levels
NT-proBNP level
Day 1 Day 3 Day 5 Day 10
R 0.499 0.779 0.675 0.622
R2 0.162 0.558 0.392 0. 315
β p Value β p Value β p Value β p Value
Predictors
Gestational age −0.495 0.013* −0.046 0.750 −0.169 0.306 −0.304 0.087
PROM −0.495 0.789 0.194 0.072 0.149 0.218 −0.104 0.416
Inotropes 0.026 0.871 0.226 0.058 0.056 0.679 0.148 0.304
Sepsis 0.170 0.239 −0.112 0.299 0.057 0.639 0.417 0.002*
Significant PDA 0.025 0.892 0.583 0.000* 0.527 0.001* 0.262 0.119
  • β represents the regression coefficient; R2 represents the multiple correlation coefficients; *Significant p values.

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