Hydrocortisone treatment for severe evolving bronchopulmonary dysplasia and cerebral haemodynamics
- G Cambonie1,
- R Mesnage1,
- C Milési1,
- A Rideau1,
- C Veyrac2,
- J-C Picaud1
- 1Neonatal Intensive Care Unit, Arnaud de Villeneuve Hospital, University Hospital of Montpellier, Montpellier, France
- 2Department of Pediatric Radiology, Arnaud de Villeneuve Hospital, University Hospital of Montpellier, Montpellier, France
- Dr Gilles Cambonie, Unité de Réanimation Néonatale, Pédiatrie II, Hôpital Arnaud de Villeneuve, 371 Avenue du Doyen G. Giraud, 34295 Montpellier Cedex 5, France; g-cambonie{at}chu-montpellier.fr
- Accepted 22 August 2008
We read with interest the paper by Rademaker et al, in which the authors raised the question of replacing dexamethasone with hydrocortisone to treat severe evolving bronchopulmonary dysplasia (BPD).1 In 2006, a national survey revealed that 91% of French neonatologists used betamethasone for delayed treatment of BPD. From October 2004 to June 2006, we treated 12 infants with betamethasone for severe evolving BPD and observed a pronounced decrease in cerebral blood flow velocities (CBFVs).2 Moreover, a quarter of these patients also …
