Red cell transport and transfusion in preterm infants
- J Gueguen3,
- A Beuchée1,2,3,
- T Gaillot3,
- P Bétrémieux3,
- P Pladys1,2,3
- 1INSERM, U642, Rennes, France
- 2Université de Rennes, LTSI, Rennes, France
- 3CHU Rennes, Pôle médico-chirurgical de Pédiatrie et de génétique clinique, Néonatologie, CHU Rennes, Rennes, France
- Dr P Pladys, Pôle médico-chirurgical de Pédiatrie et de génétique clinique, Néonatologie, CHU Rennes, Laboratoire INSERM U642 de traitement du signal et de l’image, université de Rennes 1, Pav. Le Chartier – 2 R H Le Guilloux – 35033 Rennes Cedex 9; patrick.pladys{at}chu-rennes.fr
- Accepted 4 September 2008
In preterm infants, cardiac output increases when haematocrit decreases.1 Red cell transport (RCT), which is the product of the cardiac output and haematocrit and represents the oxygen-carrying capacity, increases after neonatal red cell transfusion for anaemia.2 3 We wanted to test if a low RCT could predict a beneficial clinical response (decrease in bradycardia frequency) to red cell transfusion. Eleven preterm infants (table 1) were studied before and 24 h after a 20 ml/kg red cell transfusion that was given based on pre-established criteria.4 Infants …
