Giving vancomycin as a continuous infusion
- Newcastle Neonatal Service, Royal Victoria Infirmary, Newcastle Hospitals NHS Trust, Newcastle upon Tyne, UK
- Dr Nicholas D Embleton, Newcastle Neonatal Service, Royal Victoria Infirmary, Newcastle Hospitals NHS Trust, Newcastle upon Tyne NE1 4LP, UK; n.d.embleton{at}ncl.ac.uk
- Accepted 30 January 2009
The recent paper advocating “a new dosage schedule” for giving vancomycin in early infancy1 confirms what others have long said is usually the most appropriate total daily dose for babies of less than 34 weeks’ gestation who are more than a week old, and focuses on the time-dependent rather than the concentration-dependent mode of vancomycin killing. Continuous infusion may prevent the risks of high peaks …
