Severe bilateral intracranial haemorrhage due to alloimmune thrombozytopenia in a premature infant
- M Wilke1,2,3,
- I Müller-Hansen2,
- D Wernet4,
- T Nägele5,
- C F Poets2
- 1Department of Pediatric Neurology and Developmental Medicine, University of Tübingen, Germany
- 2Department of Neonatology, University Children’s Hospital, University of Tübingen, Germany
- 3Section for Experimental MR of the CNS, Department of Neuroradiology, University of Tübingen, Germany
- 4Department of Transfusion Medicine, University of Tübingen, Germany
- 5Department of Neuroradiology, University of Tübingen, Germany
- Correspondence to Marko Wilke, Department of Pediatric Neurology and Developmental Medicine, University Children’s Hospital, Hoppe-Seyler-Str. 1, 72076 Tübingen, Germany; Marko.Wilke{at}med.uni-tuebingen.de
- Accepted 9 February 2009
A boy weighing 1310 g was born by caesarean section at 30 2/7 weeks’ gestation due to premature contractions. Fetal ultrasound 24 hours prior to delivery was normal. Postnatal cardio-pulmonary adaptation was poor and petechiae were noted. Thrombocytopenia (7.000/μl) and anaemia (7 g/dl) were present requiring transfusion of thrombocytes and packed red blood cells. Following detection of intracranial haemorrhage by ultrasound (fig 1), cranial MRI was done at 8 h of age on a 1.5T MR scanner (Philips, …
