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Arch Dis Child Fetal Neonatal Ed doi:10.1136/adc.2006.101717

Angiotensin converting enzyme-inhibitor fetopathy: Long term outcome

  1. Guido F Laube (guido.laube{at}kispi.unizh.ch)
  1. University Children's Hospital Zurich, Switzerland
    1. Markus J Kemper (kemper{at}uke.uni-hamburg.de)
    1. University Children's Hospital Zurich, Switzerland
      1. Gregor Schubiger
      1. Children's Hospital Lucerne, Switzerland
        1. Thomas J Neuhaus (thomas.neuhaus{at}kispi.unizh.ch)
        1. University Children's Hospital Zurich, Switzerland
          • Published Online First 6 February 2007

          Abstract

          Fetal exposition to angiotensin-converting-enzyme- inhibitors (ACEI) is associated with increased neonatal morbidity and mortality. Long-term follow-up in 3 patients after fetal ACEI exposition revealed impaired renal function in two, severe hypertension and proteinuria in one and isolated polycythaemia in 3 patients. Careful long-term follow-up in children with ACEI-fetopathy is recommended.

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